impact of pharmaceutical impurities in ecstasy tablets: gas chromatography-mass spectrometry study
نویسندگان
چکیده
in this study, a simple and reliable method by gas chromatograph–mass spectrometry (gc–ms) was developed for the fast and regular identification of 3, 4-mdma impurities in ecstasy tablets. in so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by gc–ms. the results revealed high mdma levels ranging from 37.6% to 57.7%. the gc-ms method showed that unambiguous identification can be achieved for mdma from 3, 4-methylenedioxyamphetamine (mda), amphetamine (am), methamphetamine (ma) and ketamine (keta) compounds, respectively. the experimental results indicated the acceptable time window without interfering peaks. it is found that gc-ms was provided a suitable and rapid identification approach for mdma (ecstacy) tablets, particularly in the forensic labs. consequently, the intense mdma levels would support the police to develop a simple quantification of impurity in ecstasy tablets.
منابع مشابه
Impact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study
In this study, a simple and reliable method by gas chromatograph–mass spectrometry (GC–MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC–MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method sh...
متن کاملImpact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study
In this study, a simple and reliable method by gas chromatograph–mass spectrometry (GC–MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC–MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method sh...
متن کاملImpact of Pharmaceutical Impurities in Ecstasy Tablets: Gas Chromatography-Mass Spectrometry Study
In this study, a simple and reliable method by gas chromatograph-mass spectrometry (GC-MS) was developed for the fast and regular identification of 3, 4-MDMA impurities in ecstasy tablets. In so doing, 8 samples of impurities were extracted by diethyl ether under alkaline condition and then analyzed by GC-MS. The results revealed high MDMA levels ranging from 37.6% to 57.7%. The GC-MS method sh...
متن کاملGas Chromatography-Mass Spectrometry
Gas chromatography (GC) is a widely applied technique in many branches of science and technology. For over half a century, GC has played a fundamental role in determining how many components and in what proportion they exist in a mixture. However, the ability to establish the nature and chemical structure of these separated and quantified compounds is ambiguous and reduced, and requires a spect...
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عنوان ژورنال:
iranian journal of pharmaceutical researchجلد ۱۵، شماره ۱، صفحات ۲۲۱-۲۲۹
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